Creating artificial liver using 3D-printing


A breakthrough in the field of 3D-technology allowed U.S. scientists to create a matrix for the blood vessels. Served as the building blocks of sugar. In earlier experiments, artificial cells died before the forming fabric. Sugar, according to the researchers, should help to resolve this problem.

Experts from the University of Pennsylvania have found a template for creating blood vessels, 3D-templates of sugar may help grow artificial organs with blood vessels, as reported by the news agency Bi-bi-si. The new method is based mainly on the so-called technology "print inside out", first printing of blood vessels takes place, after which they gradually built up around the fabric. Easily soluble lattice of sugar prevents rejection of artificial internal organs of the body, helping them to get accustomed to it. The whole process is quite fast, does not require a huge financial cost.

In the information published in the scientific journal Nature Materials, says that scientists have been experimenting for a long time with 3D-printed cells and blood vessels, creating a neat tissue layer by layer, using a synthetic cell. But in most cases, artificial cells were dying before the fabric began to take shape. Sugar should help eliminate this problem, as the researchers believe.

At the moment, scientists have managed to create a network of blood vessels with a wall thickness of 1 mm. Scientists claim that would demonstrate the ability to create a thicker fabric, which in turn will receive future full donor organs. Active work on the creation of in vitro liver, which could be used as a graft.

Recall that the 3D-printing first appeared in 1996 with the world’s first 3D-printer Z402. Today, printing can be performed in different ways and with different materials, but the base of each of these is the general principle - layerwise build a solid object using the virtual 3D-model. These technologies are already widely used for rapid prototyping and rapid manufacturing. But the use of 3D-printing for growing artificial organs were examined by scientists for the first time.

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