Cartilage is able to repair itself?


31/07/2008

Scientists have discovered that a certain type mice has tremendous natural ability to regenerate cartilage. The study of this phenomenon may help to significantly improve and facilitate the treatment of damaged cartilage in humans.

Researchers at Oregon Health and Science University (Oregon Health & Science University), led by Jamie Fitzgerald (Jamie Fitzgerald), a professor at Oregon College of Medicine found that a certain strain of male mice (MRL / MpJ) have an innate ability to repair their own knee cartilage .

Knee pain - one of the most common musculoskeletal problems that people complain about doctors. In humans, the damaged cartilage heals poorly, and sometimes deal ends degeneration of cartilage and osteoarthritis. This is - a huge clinical problem. It is estimated that one quarter of the adult population in 2020 will suffer from one or another type of arthritis.

Knee injury - a serious problem for professional athletes. The National Football League has given scientists even grant for the initial studies because in their view, damage to cartilage can be career-ending for football players.

For example, a basketball player Greg Oden (Greg Oden) missed the season with the Blazers because of cartilage injuries and golf champion Tiger Woods (Tiger Woods) for two months, missed the game after undergoing surgery on damaged cartilage left knee.

Scientists have carefully studied knee injuries in 150 mice. Three months after damaging knee cartilage, male MRL mice have replaced a large number of injured tissue healthy cartilage.

Little Chris (Chris Little), director of "Raymond Purves Bone and JRL" (Australia) and one of the scientists involved in the project, said that this discovery is extremely important for human health. "The research that we conducted, is an initial but important step in finding new ways to treat the injured cartilage," - said Little.

The next step is understanding why mice are able to restore the cartilage in your knees. The researchers want to find out which genes and proteins are involved in the recovery process, and try to find similar genes and proteins in humans.

Fitzgerald became interested in studying the MRL-mice in 2005. He found that this type of mice is able to heal ear wounds without scarring, including replacing cartilage, hair follicles, skin and blood vessels. Receive a daily hot news - download news ticker, be aware of world events.

Original: Eurekalert.org


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