Genetic mutations are not associated with the development of disease


The fact that the man is not perfect, said by the ancient sages. This is confirmed by modern research: the scientists found that each person has certain genetic variations that determine its susceptibility to certain diseases or abnormal development. However, strangely enough, these defects are the cause of the disease is much less common than they should be.

Scientists have long known snake that everyone has a specific set of damaged DNA variations, and not all of them cause disease, but there are no statistics on the number of these mutations and the likelihood of developing health problems because of them. Now British scientists have little to clarify the situation with these cryptic genetic variation: they have more accurate data on their numbers and made a general list of potentially hazardous to human health variations.

As estimated by scientists from Cambridge and Cardiff universities, healthy people have an average of 400 dangerous genetic variation. However, the results of their study showed that a genetic disease develops maximum of one in ten.

The study used a database of DNA mutations developed by the team of Professor David Cooper for 15 years. It is likely that in the future if scientists decide to hold a large-scale genetic research, the number of dangerous variations replenished.

British scientists have found that the most potentially disease-causing genetic mutations or appear later in life, or they cause disease occur gently, in invisible form. The researchers found that numerous DNA damage and even completely inactivated proteins in general does not impact on the health of most people.

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