Nanoparticles with bee venom kill HIV


09/03/2013

The nanoparticles carrying one of the toxins, which is part of the bee venom destroys virus imunnodifitsita person without harming the surrounding cells, as scientists have found from medical school at Washington University in St. Louis. This discovery is an important step towards a vaginal gel that prevents the spread of HIV, the virus that causes AIDS.

"We hope that in those regions where HIV is spread with the speed of the epidemic, people will be able to use this gel as a precautionary measure to prevent infection," - said Dr. Joshua Hood.

This study is published in the journal Antiviral Therapy.

Bee venom contains a toxin called Melitina which bore holes in the protective layer surrounding the HIV and other viruses. Large doses of unbound melittine can cause serious harm. In addition to antiviral therapy, the author Samuel Wickline, has demonstrated that nanoparticles with Melitina effective in killing cancer cells.

In this study, researchers found that the charged Melitina nanoparticles do not harm normal cells. This is protective bumpers have been added to the surface of the nanoparticles. In the event of a collision with a normal cell, which is much larger in size, these nanoparticles are simply bounce off them. According to its dimensions HIV less than these nanoparticles, so it passes easily between the bumpers and contacts the surface of the nanoparticles, where it waits for the toxin.

"We attack the hereditary physical property of HIV," - said Hood. "Theoretically, there is no way to adapt the virus to such attack."

Original: News.wustl.edu


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